AGRICULTURE AND ENVIRONMENT BIOTECHNOLOGY COMMISSION

 

HORIZON SCANNING SUB-GROUP

 

NOTE OF A MEETING ON 24 APRIL 2001

AT THE HUB, EDINBURGH

WITH MEMBERS OF THE

ENGINEERING GENESIS WORKING GROUP OF THE

SOCIETY RELIGION AND TECHNOLOGY PROJECT

OF THE CHURCH OF SCOTLAND

 

Note: These are the views of the sub-group, not necessarily those of the full Commission

 

Present:

 

Engineering Genesis Working Group of the Church of Scotland Society Religion and Technology Project

Donald Bruce (Convenor)

Mike Appleby

Ann Bruce

John Eldridge

Michael Northcott

Joyce Tait

 

AEBC

Ed Dart

Julie Hill (Convenor)

ChiChi Iweajunwa

Derek Langslow

Roger Turner

 

Anne Packer (Secretary)

 

 

Introductions

1.      Julie Hill welcomed the members of the Engineering Genesis Working Group of the Society, Religion and Technology Project (SRT) of the Church of Scotland for an informal discussion.  She outlined the origin of the AEBC and described the horizon scanning group’s work, which was one of the three major work-streams for the Commission within its strategic overview of biotechnology for agriculture and the environment.  The group aimed to publish a paper by the end of 2001.  The AEBC group welcomed the opportunity for discussions with the Church of Scotland group, which had the benefit of considerable experience.   AEBC would particularly welcome input on particular aspects to keep in mind during its work.

 

2.      Donald Bruce described the work of the Church of Scotland SRT Project since its establishment in 1970, using slides which are attached as an annex to this note.  The Engineering Genesis working group was set up in December 1993 to study the ethical and social implications of genetic engineering in animals, plants and micro-organisms, which were seen as an important emerging issue in technology.

 

3.      The group's approach follows SRT's pattern of many years, seeking a constructive means of dialogue on contentious issues.  The group brought together a broad range of expertise and members with diverse views. Its approach was to establish a multi-faceted understanding of the issues, drawing from the range of specialisms.  Rather than seeking consensus, it gave space to examine different perspectives, seeing where agreement and disagreement existed, and exploring the values and assumptions which underlay the various viewpoints.  Donald Bruce said that in a number of ways the group prefigured the concept of the AEBC.  In its book ‘Engineering Genesis’, published by Earthscan in November 1998, the group called for the setting up of such a body as AEBC.  The book indicates areas of agreement but also presents mutual critiques.

 

4.      The working group was currently working on a revised edition of ‘Engineering Genesis’, which cover the same issues but would take especial account of developments over GM food and ecological risk and in applications relating to developing countries such as vitamin A rice.

 

5.      The book was aimed at the general public, and the SRT Project has also submitted reports to the Church of Scotland General Assembly. There had been reports on patenting and on cloning in 1997, and GM food in 1999.  A report on GM animals would be submitted for the next Assembly in May 2001. In order to make policy recommendations to the church, Donald Bruce had made specific interpretations on some issues where the book had left options open.

 

Issues discussed

6.      Donald Bruce said they had identified some key value criteria which people frequently used to evaluate genetic modification of crops and foods.  These are set out in paragraph 6 of the annex. 

 

7.      He also explained how, on the basis of the group's work, he had developed the concept of biotechnology as a social contract, particularly in relation to its future directions. Societal approval of what scientists proposed was no longer something to be taken for granted. Trust was conditional. Society seemed prepared to accept a sensitive new developments on technology provided certain conditions were fulfilled.  Some of these conditions are described in paragraph 7 of the annex.

 

8.      Some of the points raised in general discussion were:

 

·        The group consider that intrinsic ethical values in relation to genetic modification were very important and not to be dismissed. They found that they are likely to be held as much by scientists in supporting genetic modification as objectors in opposing it.  It was not a question of one being rational and the other irrational, but of different modes of rationality - instrumental and value-based reasoning were in themselves equally rational.

 

·        Thus, ethical questions frequently emerged when people initially thought issues were simply technical ones, for example in patent applications, where some held intrinsic concerns about intellectual property applied to genes and to living organisms.

 

·        Similarly, food for the developing world was not just a question of what are the best techniques to grow food to meet the demands of a growing population. Wider issues of access to land and food, poverty, inequity and maldistribution were all highly relevant.

 

·        There could also be intrinsic problems with balance of power in relation to the promotion of genetic modification.

 

·        An ideology of ‘genetic essentialism’ was sometimes associated with views that it was intrinsically wrong to do genetic modification. This holds that people should not interfere in principle with genetic make-up because this was part of the essence of the organism.  It differs from a view which asks what is the function of the gene in the organism, and evaluates interference on the functional harm or benefit it causes.

 

·        In the debates on crops, social science researchers drew the distinction between ‘value based’ and ‘interest based’ frameworks.   If someone approaches an issue on the basis of whether they perceive it to be in their interests, they may be moved in their opinion, either way, by arguments about benefits or harms. If they approach the issue on a value basis, however, they were much less likely to be changed by being told that something they objected to on principle was "good for them".  The biotechnology industry had tended to ignore the fact that people often had unspoken fundamental assumptions, and had reacted to what were value based concerns about GM crops as if they had been interest based. 

 

·        Many people had become suspicious of scientists and politicians in this area, which raised questions of how to generate or reconstruct trust.

 

·        It was important to encourage understanding of issues in the media, to broaden the debate – understanding the context reduced the tendency to demonise issues.

 

·        People had talked about the ‘intrinsic value’ of animals at the AEBC public meeting the previous day. There seemed to be no common framework for evaluation of acceptability.  People had a range of views about what health, pain, dignity and ‘naturalness’ mean in the context of animal welfare.  Some people were also beginning to consider what the intrinsic value of plants might mean.  The group's work had considerable thought to the extent to which changing the attributes of both farm and experimental animals could be an affront to dignity, whether or not pain was involved. The recent example of GM primates took this question even further.

 

·        There would be substantial environmental issues if there were GM insects.

 

·        It could be useful to consider the ‘positive agenda’ for biotechnology, perhaps looking at the most positive developments that might come.

 

·        There are other sustainable ways of doing agriculture that have been ignored in the current tendency to polarise the debate into GM/conventional vs organic.  There may in future be a greater emphasis on different forms of extensive farming.

 

·        More work could be useful on people’s perception, and why some issues seemed not to be perceived in advance and then caused considerable uncertainty and ambivalence. 

 

·        Discussing GM in relation to the third world raised complex issues.  There could be an argument for providing a platform in the developed world for products and traits which could be needed in the third world like stress and disease tolerance crops or increased yields, but which are not needed here.  Some developments were coming from within countries themselves.  Each country, however, contained different voices from people with very different interests.  It was important to be clear in whose interests GM developments would be made.  The Rockefeller foundation was active in making available for the third world intellectual property regarding GM developments which was held by industrial countries.

 

9.      Donald Bruce and Joyce Tait offered to send some reports prepared by the Church of Scotland project and by SUPRA (Scottish Universities Policy Research and Advice network) to the AEBC group for information.  Closing the meeting, Julie Hill thanked everyone attending for participating in a very fruitful exchange of ideas.

 

 

 

AEBC Secretariat

 


ANNEX: TEXT OF PRESENTATION GIVEN BY DR DONALD BRUCE

 

 

 

ENGINEERING GENESIS

Ethical Issues in the Genetic Engineering in Animals, Plants and Micro-Organisms

Overview of the Study

Dr Donald M. Bruce

Society, Religion and Technology Project, Church of Scotland

 

1. Society Religion and Technology Project

Set up in 1970 by the Church of Scotland, with a full time scientific director

 

To explore ethical issues arising from current technology

 

To engage scientists and technologists in discussion on the ethical and social implications of their work

 

To present well independent, informed and balanced views to policy makers, Government, EU, etc.

 

To stimulate discussion within the Church & in civil society

 

2. Working Group Members

Dr Mike Appleby, BSc, PhD

       Senior Lecturer in animal welfare, Edinburgh University.

Prof. David Atkinson, BSc, PhD, FIBiol, MIEEM, MIPSS

       Deputy Principal, Scottish Agricultural College, Edinburgh.

Mrs Ann Bruce, BSc, MSc, Dip AIM (Co-editor, Researcher and Secretary)

       Scientific Administrator Roslin Institute

Dr Donald Bruce, BSc, PhD, Dip.Th (Co-editor, Convenor)

       Director: Society, Religion and Technology Project, Church of Scotland.

Prof. John Eldridge, BSc, PhD

       Professor of Sociology, Glasgow University.

Rev. Dr Michael Northcott, BA, MA, PhD

       Reader in Christian Ethics & Practical Theology, Edinburgh University

Prof. Joyce Tait, BSc, PhD

       Visiting Professor, Research Centre for Social Sciences, Edinburgh University

Prof. Ian Wilmut, OBE, BSc, PhD

       Principal Investigator, BBSRC Roslin Institute, Edinburgh

Prof. Michael Wilson, BSc, PhD, MIBiol, CBiol

       Deputy Director, Scottish Crop Research Institute, Invergowrie.

Prof. Peter Wilson, CBE, FRSE, MSc, PhD, FIBiol

       General Secretary, Royal Society of Edinburgh

 

3. Case studies

1.  Pseudomonas -  genetically modified soil bacteria

2.  Abiotic Stress - genetically modifying plants for harsh environments

3.  Novel oils from genetically modified oilseed

4.  Medical proteins from plants, using genetically modified plant viruses

5.  Genetically modified insect viruses as pesticides

6.  Genetically Modified Tomatoes

7.  BST - boosting milk yields with hormones produced in genetically modified bacteria

8.  Pharmaceuticals from milk - producing pharmaceuticals in sheep milk

9.  Xenotransplantation - organ transplants from genetically modified pigs

10. Modelling human disease - genetically modified mice as models of human diseases

11. Dolly mixture - cloning by nuclear transfer to improve genetic engineering in animals

 

 

4. Main ethical issues – Chapters in ‘Engineering Genesis’

Chapter 3            Underlying issues and ethical perspectives on genetic engineering

Chapter 4            Genetic Engineering and Animal Welfare.

Chapter 5            Weighing up Animal Ethics and Human Benefit

Chapter 6            Transgenic Food

Chapter 7            Environmental risks from genetically modified organisms

Chapter 8            Patenting and Biotechnology

Chapter 9            Genetic Engineering and the Third World

Chapter 10            The Social Context of Genetic Engineering

Chapter 11            Final Reflections

 

 

5. Some key themes in Engineering Genesis

 

1.      the need to evaluation of intrinsic ethical questions as well as consequential ones

 

2.      the ethical significance of mixing genes across species

 

3.      the promise of genetic engineering is more variable than it might appear

 

4.      the use and suffering of animals, in new and also existing practices

 

5.      the difficulty of balancing medical research against animal use

 

6.      the significance of transgenic material in food, and the need to label as such

 

7.      the balance of technological and "traditional" approaches to agriculture

 

8.      the importance of wider ecological concerns, not merely the main intended effect

 

9.      the balance of environmental and other benefits and relatively unpredictable hazards

 

10.  at what level of knowledge can risk regulation can become less precautionary?

 

11.  the effect of gradualism - making major unintended changes by small logical steps

 

12.  the role of commercial drivers in genetic engineering, e.g. in patenting and food

 

13.  the polarisation of views on whether living organisms should be patented

 

14.  the role of social and political power structures in the direction of biotechnology

 

15.  the importance of recognising the underlying value systems of the different players

 

16.  the tendency to an unjust sharing of costs and benefits, and of winners and losers

 

17.  the difficulty of applying genetic engineering to the needs of developing countries

 

18.  the need for greater discussion and public accountability

 

19.  the need for a statutory biotechnology ethics commission

 

6. Key Value Criteria used to Evaluate GM Foods

 

·        Theological/philosophical - is switching genes just wrong?

 

·        Ideological - industrial vs organic agriculture

 

·        Risk - what is being precautionary enough?

 

·        Scientific rationality - technological progress

 

·        Commercial - economic growth, jobs, competition

 

·        Resource - helping to feed the world

 

·        Development - global justice for the poor

 

·        Control / Participation - who decides / against what criteria?

 

 

7. Technology as a Social Contract *

 

Society is prepared to accept a sensitive new technology and adjust somewhat to its demand, provided certain conditions are fulfilled

 

·        Familiarity: is it familiar and understood, socially embedded?

 

·        Values: does it uphold or challenge basic values

 

·        Comparison: has something like it gone wrong before ... or proved reliable?

 

·        Control: how much do we feel in control of the risk?

 

·        Trust: how much do we trust those in control,

 

·        Shared vision: How much do we share their values, motivations, goals?

 

·        Voluntary or imposed risk?

 

·        Frequency of risk: if it’s too frequent it’s unacceptable

 

·        Magnitude of risk: much greater aversion to high consequence risks

 

·        Immediacy of risk: is it noticeable or creeping up insidiously?

 

·        Tangible Benefits to Consumer

 

8. GM Food failed the Social Contract *

 

·        Unfamiliar and sensitive

 

·        Challenged basic values about genes and species

 

·        Suspicion of unnecessary scientific tampering

 

·        Risk compared with BSE or ecological accidents

 

·        Not in control and no trust in those who are

 

·        Suspicion of commercial motivation

 

·        No choice: risk unavoidable

 

·        Imposed risk with no tangible benefit

 

 

* Bruce, D. M. (2002) A Social Contract for Biotechnology- Shared Visions for Risky Technologies? J. Agric.Food Ethics, in preparation.

   Bruce, D. M. (2002) Playing Dice with Creation, in  Szerszynski, B. and  Deane-Drummond, C. (eds) “Reordering Nature”, T&T Clark, Edinburgh (in press)

† Bruce, D. and A. (1998) Engineering Genesis, chaps.3 and 10, Earthscan, London

‡ Tait, J. E. (2001) More Faust than Frankenstein: The European Debate about Risk Regulation for Genetically Modified Crops, J. Risk Research (in press)

 

Dr Donald M. Bruce

Society, Religion and Technology Project

Church of Scotland

John Knox House, 45 High Street,

Edinburgh EH1 1SR, Scotland

 

Tel.: +44 131 556 2953

Fax : +44 131 556 7478

E-mail : srtp@srtp.org.uk

Website : http://www.srtp.org.uk